AI-segmentation… SEQUOIA 8 Feb 202413 Feb 2024 automated multiclass SEgmentation, QUantification, and visualizatiOn of the dIseased Aorta on hybrid PET/CT SEQUOIA is an automated pipeline for aortic PET/CT studies. First, it segments the ascending aorta, aortic arch,…
AI-PET denoising… Parameter-Transferred Wasserstein Generative Adversarial Network (PT-WGAN) for Low-Dose PET Image Denoising 1 Jan 202413 Feb 2024 Task: Low-dose PET image denoising via a GAN method Description: A hybrid 2D and 3D parameter-transferred Wasserstein GAN PT-WGAN model for low-dose PET image denoising. The model's performance is a…
AI-PET attenuation… Whole Body PET Attenuation Correction Map Synthesizing using 3D Deep Networks 1 Jan 202413 Feb 2024 Task: Whole body attenuation map generation using 3D U-Net generative adversarial networks (GANs) Description: The model is initially trained as a 3D U-Net to learn the mapping from non attenuation…
AI-segmentation… NanoMASK: Nanomedicine Multi-modal AI-based Segmentation for PharmacoKinetics 1 Jan 202413 Feb 2024 Task: Automatic organ and tumor segmentation for nanomedicine pharmacokinetic studies. Description: NanoMASK model is a 3D U-Net adapted deep learning tool capable of rapid, automatic organ segmentation of multimodal imaging…
AI-NeuroImaging… JuST_BrainPET: Juelich Segmentation Tool for Amino Acid PET Brain Tumor Segmentation 1 Jan 202422 Feb 2024 Task: Automated Brain Tumor Detection and Segmentation for Treatment Response Assessment Using Amino Acid PET Description: JuST_BrainPET: Juelich Segmentation Tool for Brain Tumor PET is a model trained for metabolic…
AI-multi-modality image fusion… Multi-modal Medical Image Fusion via Multi-dictionary and Truncated Huber Filtering 1 Jan 202413 Feb 2024 Task: Multi-modal medical image fusion Description: The model is comprised of a novel medical image fusion algorithm based on multi-dictionary convolutional sparse representation (CSR) for retaining useful information while achieving…
AI-cardiac… TAI-GAN: Temporally and Anatomically Informed GAN for early-to-late frame conversion in dynamic cardiac PET motion correction 1 Jan 20249 May 2024 Task: To synthesize a reference late cardiac Rb-82 PET image frame from a set of respective early PET image frames for improved inter-frame registration, motion correction and myocardial blood flow…
AI-NeuroImaging… AI-imputed tau-PET: Synthesizing PET images of tau pathology from cross-modal neuroimaging using deep learning 1 Jan 202423 Feb 2024 Task: To impute tau-PET images from more widely available cross-modality imaging inputs Description: The AI-imputed tau-PET model is a 3D Dense-U-Net Convolutional Neural Network (CNN) that imputes synthetic tau-PET images…
AI-NeuroImaging… brainPETNR: Brain PET Noise Reduction using a Frequency Attention Network 1 Jan 202422 Feb 2024 Task: Denoising of low-activity PET reconstruction of [11C]PiB and [18F]FE-PE2I images in neurodegenerative disorders Description: The brainPETNR framework utilizes a Frequency Attention Network (FAN) model for denoising of low-activity reconstructed brain…
AI-classification… Automated Detection of Focal Cortical Dysplasia With the FCDdetection Model Using Quantitative Multimodal Surface-Based Features 1 Jan 202423 Feb 2024 Task: Detection of Focal Cortical Dysplasia (FCD) lesions by combining quantitative multimodal surface-based features with machine learning and to assess its clinical value. Decription: The FCDdetection model is a neural…
AI-lung cancer… A Bayesian approach to tissue-fraction estimation for oncological PET segmentation 1 Jan 202426 Feb 2024 Task: Semi-automated tissue-fraction estimation-based lesion segmentation from human PET images for quantitative assessments of oncologic diseases. Description: The proposed model implements a novel Bayesian approach to tissue-fraction estimation (TFE) for oncological…
AI-PET synthesis… CycleGAN-QSDL: Quasi-supervised deep learning for super-resolution PET 1 Jan 202419 Feb 2024 Task: Generate synthetic high-resolution PET images from low-resolution PET images Description: QSDL is a quasi-supervised deep learning method, which is a new type of weakly-supervised learning methods, to recover high-resolution…
AI-classification… CGAN-based 18F-Florbetaben PET Data Augmentation for Enhanced Classification of Amyloid-beta distributions 1 Jan 202424 Feb 2024 Task 1: Improve Data Augmentation (DA) of a limited training set of 18F-Florbetaben (18F-FBB) PET images by synthesizing additional realistic 18F-FBB PET images using a Conditional Generative Adversarial Network (CGAN)…
AI-Large Language Models (LLMs)… Automatic Personalized Impression Generation for PET Reports Using Large Language Models(LLMs) 1 Jan 202413 Feb 2024 Task: Automatic Impression Generation for PET Reports Using Large Language Models (LLMs) Description: A collection of twelve open-source language models fine-tuned on a corpus of 37,370 retrospective PET reports were…
AI-outcome prediction… nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation 1 Jan 202420 Feb 2024 nnU-Net (v2) is a deep learning-based segmentation method that automatically configures itself, including preprocessing, network architecture, training and post-processing for any new task in the biomedical domain. The key design…
AI-NeuroImaging… DaT-SPECT-Segmentation: A tissue-fraction estimation-based segmentation framework for quantitative dopamine transporter SPECT 1 Jan 202425 Feb 2024 Task: Fully automated tissue-fraction estimation-based segmentation of the caudate, putamen, and Globus Pallidus (GP) from human brain DaT-SPECT images for quantitative assessments of Parkinson's Disease. Description: The DaT-SPECT-Segmentation model estimates the…
AI-PET denoising… FAN: Frequency Attention Network for Blind Noise Removal in Real Images 1 Jan 202421 Feb 2024 Task: Blind Noise Removal in Real Images Description: The FAN (Frequency Attention Network) model implements a method for blind image denoising that combines frequency domain analysis and attention mechanism, The…
AI-pulses discrimination… DMLLT Detector Pulse Discriminator – A supervised machine learning approach for shape-sensitive detector pulse discrimination in positron annihilation lifetime spectroscopy (PALS) applications 1 Jan 202413 Feb 2024 Task: Detector pulse discrimination in positron annihilation lifetime spectroscopy (PALS) Description: A supervised machine learning (ML) model based on a naive Bayes classification model using a normally distributed likelihood as…
AI-outcome prediction… ICARE: Individual Coefficient Approximation for Risk Estimation model for outcome prediction in head and neck PET/CT 1 Jan 202419 Feb 2024 Task: Recurrence Free Survival (RFS) Prediction in Head and Neck Tumors segmented from 18F-FDG PET/CT images Description: ICARE is a publicly available novel binary-weighted model operating on radiomic features calculated…
AI-PET synthesis… SC-GAN: 3D self-attention conditional GAN with spectral normalization for multi-modal neuroimaging synthesis 1 Jan 202413 Feb 2024 Task: Multimodal (PET & multi-modal MR) 3D medical image synthesis Description: A novel 3D conditional generative adversarial network (GAN) designed and optimized for the application of multimodal 3D neuroimaging synthesis.…
AI-PET reconstruction… Model-based deep learning PET image reconstruction using FBSEM 1 Jan 202413 Feb 2024 Task: Bayesian Iterative PET image reconstruction Description: The model consists of a forward-backward splitting algorithm to integrate deep learning into maximum-a-posteriori (MAP) positron emission tomography (PET) image reconstruction. The MAP…
AI-PET reconstruction… Iterative PET Image Reconstruction Using CNN Representation 1 Jan 202413 Feb 2024 Task: Iterative PET Image reconstruction Description: The model employs a deep residual convolutional neural network to improve PET image quality by using the existing inter-patient information. An innovative feature of…
free (w/ or w/o commercial version)… MAMBA 5 Nov 20235 Nov 2023 Multi-pAradigM voxel-Based Analysis: a computational cookbot The Matlab toolbox MAMBA is designed for the flexible application of statistical voxel-based (VB) analysis in different scenarios in medical imaging and radiation oncology. It provides…
free (w/ or w/o commercial version)… Musiré 1 Nov 20232 Nov 2023 Multimodal simulation and reconstruction framework for the radiological imaging sciences Musiré is a software-based workflow for managing the execution of simulation and image reconstruction for SPECT, PET, CBCT, MRI, BLI…
free (w/ or w/o commercial version)… Dynamic PET 31 Oct 202331 Oct 2023 Dynamic positron emission tomography (PET) analysis Dynamic PET is designed for voxelwise analysis of reconstructed dynamic positron emission tomography (PET) scans, and also supports regional analysis. Dynamic PET provides a command line…
free (w/ or w/o commercial version)… Bloodstream 31 Oct 2023 A PET BIDS blood-processing tool Bloodstream is a simplified and automated pipeline designed for PET studies to process blood data [1,2] in BIDS (Brain Imaging Data Structure) format [3]. The bloodstream package…
free (w/ or w/o commercial version)… Magia 30 Oct 202330 Oct 2023 Automated Brain PET Analysis Pipeline Magia is an automated processing pipeline for brain PET studies. Magia uses FreeSurfer to parcellate the brain into anatomical regions of interest, and performs kinetic…
free (w/ or w/o commercial version)… STARE 29 Oct 202331 Oct 2023 Source-to-Target Automatic Rotating Estimation STARE, Source-to-Target Automatic Rotating Estimation, is a MATLAB package for non-invasive estimation of the net influx rate (Ki) of irreversible Positron Emission Tomography (PET) radiotracers and…
free (w/ or w/o commercial version)… mfEVolve™ 28 Oct 202328 Oct 2023 Research Software for Multi-Tracer PET Imaging and Kinetic Analysis mfEVolve™ is a research-only software tool designed to facilitate multi-tracer and quantitative dynamic PET research studies by providing tools for processing,…
free (w/ or w/o commercial version)… NiftyPAD 26 Oct 202326 Oct 2023 Neuroimaging for the Prevention of Alzheimer's Disease NiftyPAD is a freely available, open source, Python-based software package for the versatile and quantitative analyses of static, full or dual-time window dynamic…
free (w/ or w/o commercial version)… FALCON 25 Oct 202325 Oct 2023 Fast Algorithms for Motion Correction FALCON is a Python-based advanced, fully-automatic PET image registration and motion correction tool designed to facilitate PET motion correction, both for head and total-body scans.…
AI-segmentation… MOOSE 25 Oct 202313 Feb 2024 Multi-organ objective segmentation MOOSE (Multi-organ objective segmentation) is a data-centric AI solution designed to streamline systemic Total-Body research by generating multilabel organ segmentations with high precision. Built on the robust…
free (w/ or w/o commercial version)… PyTomography 19 Oct 202319 Oct 2023 A Python Library for Quantitative Medical Image Reconstruction PyTomography is an open-source, GPU-accelerated python library providing both extensive system modeling for SPECT/PET systems as well as associated reconstruction algorithms for…
AI-Prostate Cancer… Automated mPCa lesion segmentation with self-configuring nnU-Net framework 12 Jun 202320 Feb 2024 An automated segmentation framework based on deep learning for metastatic prostate cancer (mPCa) lesions in whole-body [68Ga]Ga-PSMA-11 PET/CT images for the purpose of extracting patient-level prognostic biomarkers. AI-tool features Disease…
free (w/ or w/o commercial version)… TriDFusion (3DF) image viewer 22 Mar 202327 Mar 2023 The TriDFusion (3DF) Image Viewer is a MATLABTM-based Multi-Fusion Imaging research software tool designed for physicians, physicist and academic researchers in medical imaging. It is a Multi-Modality & Multidimensional DICOM Image…
free (w/ or w/o commercial version)… RT-UTILS: A minimal Python library for RT Struct manipulation 22 Mar 202327 Mar 2023 RT-Utils has been developed to allow physicians and other users to view the results of segmentation performed on a series of DICOM images. It allows you to create or load…
free (w/ or w/o commercial version)… Open KM Initiative 7 Aug 202227 Mar 2023 The Open Kinetic Modeling (OpenKM) Initiative is aimed at opening up more educational opportunities and research resources on tracer kinetic modeling in the technical community of molecular imaging. The OpenKM…
free (w/ or w/o commercial version)… imlook4d 8 Mar 202227 Mar 2023 Imlook4d is a software tool for visualization of medical images (2D), volumes (3D) and time-dependent volumes (4D). Imlook4d is written in Matlab, which means that it has to be installed…
free (w/ or w/o commercial version)… DEPICT 7 Mar 20227 Mar 2022 A Basis Pursuit Kinetic Modelling Software DEPICT (data-driven estimation of parametric images based on compartmental theory) is a software package written in Matlab 6.5 for the analysis of kinetic radiotracer data. The method…
free (w/ or w/o commercial version)… APPIAN 4 Mar 20224 Mar 2022 APPIAN (Automated Pipeline for PET Image ANalysis) is an open-source automated software pipeline for analyzing PET images in conjunction with MRI. The goal of APPIAN is to make PET tracer…
free (w/ or w/o commercial version)… SAKE 3 Mar 20223 Mar 2022 Spectral Analysis Kinetic Estimation (SAKE): an integrated tool for quantification of PET data. SAKE is an open-source software designed for the easy application of spectral analysis in PET kinetic modeling…
free (w/ or w/o commercial version)… MIRDsoft.org (Radiation Dosimetry Community Platform) 2 Mar 20222 Mar 2022 MIRDsoft.org is a community platform of next generation applications for deriving, reporting, and managing dosimetry data in nuclear medicine, computed tomography, and hybrid imaging. The platform is focused on designing,…
free (w/ or w/o commercial version)… CILViewer 1 Mar 20221 Mar 2022 A simple Viewer for 3D data built with VTK and Python. The interactive viewer CILViewer2D provides: Orthoslicer (slice in x/y/z direction)keyboard interaction'x' slices on the YZ plane'y' slices on the…
free (w/ or w/o commercial version)… NAPARI 28 Feb 20221 Mar 2022 Multi-dimensional image viewer for python napari is a fast, interactive, multi-dimensional image viewer for Python. It’s designed for browsing, annotating, and analyzing large multi-dimensional images. It’s built on top of Qt (for the…
free (w/ or w/o commercial version)… Brain PET Sim + Recon 25 Feb 202225 Feb 2022 A C++ & Matlab-based PET simulation and reconstruction software, enabling realistic brain simulations, e.g. dynamic PiB PET imaging, based on the system matrix of the advanced brain-dedicated High Resolution Research…
free (w/ or w/o commercial version)… PET Sim & Recon 25 Feb 202221 Mar 2023 A Matlab-based PET simulation and reconstruction framework with analytical modeling of system matrix, capable of incorporating various degrees of spatial resolution's Point Spread Function (PSF) modeling. Synthetic NEMA NU2 true…
commercial-only… QUAD (Cedars Sinai Quantitative Diagnostic Software Group) 17 Feb 202217 Feb 2022 The Quantitative Diagnostic Software Group (QUAD) of the Department of Medicine at Cedars-Sinai, USA, seeks to develop software to allow computers to process and analyze three-dimensional images of the heart in…
free (w/ or w/o commercial version)… OMEGA 1 May 202114 May 2021 OMEGA is an open-source MATLAB/GNU Octave Emission and Transmission Tomography Software. The purpose of OMEGA is twofold. It has been created and maintained by Ville-Veikko Wettenhovi. OMEGA is designed primarily…
free (w/ or w/o commercial version)… FIREVOXEL 1 Mar 20213 Jul 2023 FireVoxel is a medical imaging software for analysis and display of medical images. The emphasis is on fitting the kinetic models to the dynamic MRI, CT, PET, and SPECT acquisitions. Also…
free (w/ or w/o commercial version)… Phantom Analysis Toolkit (PAT) – Cloud-based service 24 Aug 202026 Feb 2022 SNMMI’s PET/CT Phantom Analysis Toolkit (PAT) Accreditation programs (e.g., Joint Commission, ACR) are increasingly requiring phantom-based PET/CT scanner measurements to provide evidence of quantitative accuracy and qualitative clinical image quality.…
free (w/ or w/o commercial version)… IAEA-NMQC 24 Aug 202024 Aug 2020 The IAEA Nuclear Medicine Quality Control (NMQC) Toolkit is a set of ImageJ (Fiji edition)-based codes developed in Java v.1.8 that allow the processing and analysis of nuclear medicine images…
free (w/ or w/o commercial version)… Mango: Multi-image Analysis GUI 15 Jun 202021 Aug 2020 Mango – short for Multi-image Analysis GUI – is a viewer for medical research images. It provides analysis tools and a user interface to navigate image volumes. Versions There are…
free (w/ or w/o commercial version)… QModeling: an Open-Source Toolbox for PET Kinetic Analysis 15 Jun 20206 Nov 2023 QModeling is a multi-platform toolbox for SPM to fit reference-region kinetic models (currently supporting SRTM, SRTM2, Patlak Reference and Logan Reference Plots) to dynamic PET imaging data. The toolbox was…
free (w/ or w/o commercial version)… SERA: Standardized Environment for Radiomics Analysis 15 Jun 202012 Aug 2020 The Standardized Environment for Radiomics Analysis (SERA) Package is a Matlab®-based framework developed at Johns Hopkins University that calculates radiomic features based on guidelines from the Image Biomarker Standardization Initiative…
free (w/ or w/o commercial version)… kinfitr: PET kinetic modeling using R 15 Jun 202012 Aug 2020 kinfitr is a package for PET Kinetic Modelling Using R. The main goal of this package is to equip PET modelers with great flexibility, while simultaneously making it easier to…
free (w/ or w/o commercial version)… itk-SNAP 15 Jun 202012 Aug 2020 ITK-SNAP is a software application used to segment structures in 3D medical images. It is an interactive software application that allows users to navigate three-dimensional medical images, manually delineate anatomical…
free (w/ or w/o commercial version)… ITK: The Insight Toolkit 15 Jun 202012 Aug 2020 Insight Toolkit (ITK), also known as Insight Segmentation and Registration Toolkit, is an open-source, cross-platform library that provides developers with an extensive suite of software tools for image analysis. Developed…
free (w/ or w/o commercial version)… CERR: Computational Environment for Radiological Research 21 Aug 201931 Mar 2021 CERR (pronounced 'sir'), stands for Computational Environment for Radiological Research. CERR is MATLAB based software platform for developing and sharing research results using radiation therapy treatment planning and imaging informatics.…
free (w/ or w/o commercial version)… Imager-4D: Viewer for dynamic PET studies with integrated Patlak and radiomics analysis 21 Aug 201912 Aug 2020 The Imager-4D is a novel PET viewer that allows the user to view dynamic PET data and to derive dynamic and radiomic parameters from that data. This includes the ability…
free (w/ or w/o commercial version)… ASIM (Analytic PET Simulator) 4 Jun 201927 Jun 2019 ASIM is a software package designed as a fast analytic simulator for positron emission scanners. This process uses a "Monte-Carlo" approach to allow the rapid generation of multiple realizations with…
free (w/ or w/o commercial version)… Occiput.io (iLang engine) 1 Feb 201927 Jun 2019 Occiput is an Open Source Tomographic reconstruction software for PET, PET-MRI and SPECT in 2D, 3D (volumetric) and 4D (spatio-temporal) in Python, using GPUs. The design of occiput.io makes it…
commercial-only… PMOD 1 Jan 201912 Aug 2020 Description: PMOD consists of a comprehensive set of user-friendly and powerful tools, each corresponding to a major task involved in image quantification. Due to their smooth interaction, the tools form…
free (w/ or w/o commercial version)… STIR (Software for Tomographic Image Reconstruction) 1 Jan 201912 Aug 2020 Description: STIR is an Open Source software for use in tomographic imaging. Its aim is to provide a Multi-Platform Object-Oriented framework for all data manipulations and corrections in tomographic imaging.…
free (w/ or w/o commercial version)… EMrecon 1 Jan 201912 Aug 2020 EMrecon is an Expectation Maximization Based Image Reconstruction Framework for Emission Tomography Data. The EMrecon project was started in 2006 as an open reconstruction software for the quadHIDAC wirechamber small animal PET…
free (w/ or w/o commercial version)… MCNP (Monte-Carlo N-Particle) Transport Code 1 Jan 201927 Jun 2019 Description: MCNP is a general-purpose Monte Carlo N-Particle code that can be used for neutron, photon, electron, or coupled neutron/photon/electron transport. Specific areas of application include, but are not limited…
free (w/ or w/o commercial version)… PyRadiomics (Radiomics Feature Extraction in Python) 1 Jan 201912 Aug 2020 PyRadiomics is an open-source python package for the extraction of Radiomics features from medical imaging. This package aims to establish a reference standard for Radiomics Analysis, and provide a tested…
free (w/ or w/o commercial version)… NiftyRec Tomography Toolbox 1 Jan 201927 Jun 2019 NiftyRec is a software for tomographic reconstruction, providing the fastest GPU-accelerated reconstruction tools for emission and transmission computed tomography. NiftyRec supports a wide range of modalities: Positron Emission Tomography (PET)…
free (w/ or w/o commercial version)… RaCaT (Radiomics Calculator) 1 Jan 201912 Aug 2020 RaCaT is an easy to use radiomic feature calculator, which provides the calculation of a large number of radiomic features for all kind of medical images, which are in compliance…
free (w/ or w/o commercial version)… EGS (Electron Gamma Shower) 1 Jan 201927 Jun 2019 Description: The EGS computer code system is a general purpose package for the Monte Carlo simulation of the coupled transport of electrons and photons in an arbitrary geometry for particles…
free (w/ or w/o commercial version)… TIRIUS (Tomographic Image Reconstruction Interface of the Universite de Sherbrooke) 1 Jan 201927 Jun 2019 TIRIUS (Tomographic Image Reconstruction Interface of the Universite de Sherbrooke) is a Qt-based user-interface software for reconstructing 3D images from data generated by real apparatus or generated by the GATE Monte…
free (w/ or w/o commercial version)… SIMIND 1 Jan 20191 Mar 2024 Description: SIMIND is a Monte Carlo simulation code supporting the description of standard clinical SPECT cameras which can be easily modified for various types of calculations or measurements encountered in…
free (w/ or w/o commercial version)… ASTRA toolbox 1 Jan 201927 Jun 2019 The ASTRA Toolbox is a MATLAB and Python toolbox of high-performance GPU primitives for 2D and 3D tomography. The supported geometries are 2D parallel, fan beam, as well as 3D…
free (w/ or w/o commercial version)… GAMoS (Geant4-based Architecture for Medicine-Oriented Simulations) 1 Jan 201927 Jun 2019 Description: GAMOS, the Geant4-based Architecture for Medicine-Oriented Simulations, facilitates the use of Geant4 by providing a simple script language that covers almost all the needs of a nuclear medicine simulation.…
free (w/ or w/o commercial version)… TomoPy (Tomographic Reconstruction in Python) 1 Jan 201912 Aug 2020 TomoPy is an open-source Python package for tomographic data processing and image reconstruction. It features image reconstruction algorithms for tomography. various filters, ring removal algorithms, phase retrieval algorithms. forward projection operator…
free (w/ or w/o commercial version)… Radiomics Tools (by M Vallieres) 1 Jan 201912 Aug 2020 A package providing MATLAB programming tools for radiomics analysis. This package contains 5 folders: 'TextureToolbox': MATLAB codes to perform texture analysis from an input 2D or 3D region of interest…
free (w/ or w/o commercial version)… PeneloPET 1 Jan 201927 Jun 2019 Description: PeneloPET is a Monte Carlo code capable of performing realistic simulations for pixelated scintillator based PET scanners. It is based on PENELOPE, a toolkit for Monte Carlo Simulation of…
free (w/ or w/o commercial version)… QSPECT 1 Jan 201931 May 2023 QSPECT is an open-source Image Reconstruction application for SPECT data. It includes Maximum Likelihood Expectation Maximization (MLEM) and Ordered Subsets Expectation Maximization (OSEM) as well as a suitable Graphical User Interface…
free (w/ or w/o commercial version)… AMIDE 1 Jan 201912 Aug 2020 AMIDE stands for “Amide's a Medical Image Data Examiner”. The package is a completely free tool for viewing, analyzing, and registering volumetric medical imaging data sets. It has been written…
free (w/ or w/o commercial version)… SimSET (Simulation System for Emission Tomography) 1 Jan 201927 Jun 2019 The SimSET package uses Monte Carlo techniques to model the physical processes and instrumentation used in emission imaging. Official Website Source Code: Link 1 & Link 2 Tutorials: Link 1…
commercial-only… MIM Software 1 Jan 201912 Aug 2020 MIM Software Inc. provides practical imaging solutions in the fields of radiation oncology, radiology, nuclear medicine, neuroimaging, and cardiac imaging. MIM offers solutions for PC and Mac® workstations, as well…
free (w/ or w/o commercial version)… FLUKA 1 Jan 201912 Aug 2020 FLUKA is a fully integrated particle physics Monte Carlo simulation package. It has many applications in high energy experimental physics and engineering, shielding, detector and telescope design, cosmic ray studies,…
free (w/ or w/o commercial version)… VMC (the Visual Monte Carlo Program) 1 Jan 201927 Jun 2019 VMC is a computer program that simulates the irradiation of the human body by external sources. It uses a voxel phantom produced at Yale University and the Monte Carlo technique…
commercial-only… OLINDA/EXM (Organ Level INternal Dose Assessment/EXponential Modeling) 1 Jan 201927 Jun 2019 OLINDA/EXM is a personal computer code for calculating organ doses and effective doses in nuclear medicine studies was developed in 2004. OLINDA/EXM, which stands for Organ Level INternal Dose Assessment/EXponential Modeling,…
commercial-only… Hermes Medical Solutions Software 1 Jan 201921 Mar 2023 Hermes Medical Solutions continuously innovates to enable faster and more personalized diagnosis and therapies in molecular imaging and nuclear medicine. For 47 years, we have empowered physicians and healthcare professionals…
commercial-only… MIRADA Medical Imaging Software Applications 1 Jan 201912 Aug 2020 Mirada Medical develops medical imaging software applications that provide simple and accessible solutions to complex image analysis problems in the diagnosis and treatment of cancer and other diseases. Through automation,…
free (w/ or w/o commercial version)… GATE (Geant4 Application for Tomography Emission) 1 Jan 201917 May 2021 Description: Geant4 Application for Tomography Emission (GATE) is an advanced open-source software developed by the international OpenGATE collaboration and dedicated to numerical simulations in medical imaging and radiotherapy. It currently…
commercial-only… CVIT (Cardiovascular Imaging Technologies) 1 Jan 201912 Aug 2020 Cardiovascular Imaging Technologies (CVIT) is a provider of cardiac specific research and technology solutions. CVIT offers a suite of software products for quantitative image reconstruction, review, analysis and kinetic modeling.…
commercial-only… OsiriX DICOM Viewer 1 Jan 201912 Aug 2020 With high performance and an intuitive interactive user interface, OsiriX is a widely used DICOM viewer across the globe. It is the result of more than 15 years of research…
free (w/ or w/o commercial version)… MIPAV (Medical Image Processing, Analysis and Visualization) 1 Jan 201912 Aug 2020 The MIPAV (Medical Image Processing, Analysis, and Visualization) application enables quantitative analysis and visualization of medical images of numerous modalities such as PET, MRI, CT, or microscopy. Using MIPAV's standard…
free (w/ or w/o commercial version)… IBEX (Imaging Biomarker Explorer) 1 Jan 201912 Aug 2020 IBEX (imaging biomarker explorer) is an open infrastructure software platform that flexibly supports common radiomics workflow tasks such as multimodality image data import and review, development of feature extraction algorithms,…
free (w/ or w/o commercial version)… 3DSlicer 1 Jan 201912 Aug 2020 3DSlicer is an open source software platform for medical image informatics, image processing, and three-dimensional visualization. Built over two decades through support from the National Institutes of Health and a…
free (w/ or w/o commercial version)… FreeSurfer 1 Jan 201918 Oct 2023 FreeSurfer is an open-source software suite for processing and analyzing (human) brain MRI images. It can support Skullstripping, Image Registration, Subcortical Segmentation, Cortical Surface Reconstruction, Cortical Segmentation, Cortical Thickness Estimation,…
commercial-only… SAAM II (Simulation Analysis and Modeling) 1 Jan 20193 Apr 2023 SAAM II is a modeling, simulation, and analysis software package, which supports the development and statistical calibration of compartmental models in biological, metabolic, and pharmaceutical systems. Used worldwide by more…
free (w/ or w/o commercial version)… CONRAD 1 Jan 201912 Aug 2020 CONRAD is a software framework for cone-beam imaging in radiology. The software package includes different simulation tools that are able to generate 4-D projection and volume data and respective vector…
free (w/ or w/o commercial version)… AIR tools II – Algebraic Iterative Reconstruction Methods 1 Jan 201912 Aug 2020 AIR tools II is a MATLAB-based package provides efficient, robust and flexible implementations of algebraic iterative reconstruction (AIR) methods for computing regularized solutions to discretize inverse problems, such as computed…
commercial-only… MedView 1 Jan 201912 Aug 2020 MedView from MedImage is an imaging exam reading software for nuclear medicine, nuclear cardiology and PET/CT. MedView can be used as a stand-alone solution or integrated with PACS. Single station or…
free (w/ or w/o commercial version)… TIGRE (Tomographic Iterative GPU-based Reconstruction) 1 Jan 201927 Jun 2019 TIGRE is a MATLAB and Python/CUDA toolbox for fast and accurate 3D tomographic reconstruction (any geometry), created jointly by University of Bath's Engineering Tomography Lab and CERN. The aim of…
free (w/ or w/o commercial version)… VSPLINE (Vector spline smoothing package) 1 Jan 201912 Aug 2020 VSPLINE package implements previously published smoothing spline algorithms. Official Website Source Code Tutorials Reference Paper
free (w/ or w/o commercial version)… LIFEx 1 Jan 201912 Aug 2020 LIFEx is a freeware enabling the calculation of a broad range of conventional, textural and shape indices from PET, MR, US and CT images. The software is written in Java…
free (w/ or w/o commercial version)… TERSE (transmission and emission reconstruction environment for SPECT) 1 Jan 201912 Aug 2020 TERSE: a transmission and emission reconstruction environment for SPECT, has been developed at the University of Michigan by Jeff Fessler and Edward Ficaro, in a collaboration between the Department of…
free (w/ or w/o commercial version)… ASPIRE (A sparse precomputed iterative reconstruction algorithm) 1 Jan 201927 Jun 2019 ASPIRE (a sparse precomputed iterative reconstruction library) is a collection of ANSI C programs for tomographic image reconstruction developed at the University of Michigan by Jeff Fessler and his students.…
free (w/ or w/o commercial version)… UCLA Tracer Kinetic Model Fitting (TKMF) Program 1 Jan 201912 Aug 2020 The Tracer Kinetic Model Fitting (TKMF) Program is a server-based tracer kinetic analysis software program that is accessible through the Internet. It provides the general capability of tracer kinetic model…
free (w/ or w/o commercial version)… Carimas 1 Jan 201912 Aug 2020 Carimas is a general medical imaging processing platform developed in Turku PET Centre in Finland. Carimas is for research use only – not for use in diagnostic procedure. Originally, Carimas…
free (w/ or w/o commercial version)… PET-RD-tools 1 Jan 201912 Aug 2020 PET-RD-tools is a collection of command line utilities for PET-MR (pre)-processing. The tools have been designed for validating and extracting raw PET data, and associated files, for the purposes of…
free (w/ or w/o commercial version)… Fiji (just as ImageJ) 1 Jan 201912 Aug 2020 Fiji is an image processing package—a "batteries-included" distribution of ImageJ, bundling a lot of plugins which facilitate scientific image analysis. Fiji is easy to install and has an automatic update function, bundles a lot of…
free (w/ or w/o commercial version)… MIAKAT 1 Jan 201912 Aug 2020 MIAKAT™ is a fully quantitative suite of analysis tools for PET neuroimaging data. The software includes functionality for motion correction of dynamic image sequences, neuoranatomical parcellation of regions of interest…
free (w/ or w/o commercial version)… XNAT (the Extensible Neuroimaging Archive Toolkit) 1 Jan 201912 Aug 2020 XNAT is an open source imaging informatics platform developed by the Neuroinformatics Research Group at Washington University. XNAT was originally developed at Washington University in the Buckner Lab, which is now…
free (w/ or w/o commercial version)… MIRT (Michigan Image Reconstruction Toolbox) 1 Jan 201927 Jun 2019 The Michigan Image Reconstruction Toolbox (MIRT) is a collection of open source algorithms for image reconstruction (and related imaging problems) written in Matlab (MathWorks Inc.) language. This software was developed…
free (w/ or w/o commercial version)… SPM – Statistical Parametric mapping 1 Jan 201912 Aug 2020 Statistical Parametric Mapping (SPM) refers to the construction and assessment of spatially extended statistical processes used to test hypotheses about functional imaging data. These ideas have been instantiated in software…
commercial-only… VivoQuant 1 Jan 201912 Aug 2020 VivoQuant® from Invicro is a DICOM compliant post-processing suite for image data combining fundamental viewing functionality with advanced analysis capabilities. VivoQuant® supports data from most imaging modalities including MR, PET, SPECT, CT,…
free (w/ or w/o commercial version)… COMKAT (COmpartment Model Kinetic Analysis Tool) 1 Jan 201912 Aug 2020 COMKAT is a MATLAB software for compartmental modeling oriented to nuclear medicine applications (PET & SPECT). It supports models of a wide range complexity including multiple injection, receptor model with…
free (w/ or w/o commercial version)… Vinci (Volume Imaging in Neurological Research) 1 Jan 201912 Aug 2020 VINCI (“Volume Imaging in Neurological Research”) was designed for the visualization and analysis of volume data generated by medical tomography systems with special emphasis on the needs for brain imaging…
free (w/ or w/o commercial version)… PETPVC: toolbox for partial volume correction in PET 1 Jan 201912 Aug 2020 PETPVC is a toolbox for partial volume correction (PVC) in positron emission tomography (PET). The package offers a method for applying partial volume correction (PVC) to positron emission tomography (PET)…
free (w/ or w/o commercial version)… PETstep & dPETstep – (dynamic) PET Simulator of Tracers via Emission Projection 1 Jan 201912 Aug 2020 PETstep is a fast analytic PET simulator designed in MATLAB environment for high throughput simulation of PET images. It allows a full simulation of a user defined activity distributions (objects)…
free (w/ or w/o commercial version)… KesnerDDG – Data-driven respiratory gating of PET list-mode data 1 Jan 201912 Aug 2020 KesnerDDG is research software that can be used for data driven respiratory motion correction in PET imaging. This software was built as a free tool to be available for researchers…
free (w/ or w/o commercial version)… QIICR (Quantitative Image Informatics for Cancer Research) 1 Jan 201912 Aug 2020 QIICR: open source imaging informatics tools based on 3D Slicer to support research workflows of the NCI Quantitative Imaging Network.QIICR is supported by the NIH National Cancer Institute ITCR program,…
free (w/ or w/o commercial version)… NiftyPET 1 Jan 201912 Aug 2020 NiftyPET is an open source Python package for image reconstruction and analysis with uncertainty estimation as well as support for high-throughput parallel processing using GPU computing. The pipeline of the…
free (w/ or w/o commercial version)… CASToR (Customizable and Advanced Software for Tomographic Reconstruction) 1 Jan 201912 Aug 2020 CASToR is an open-source multi-platform project for 4D emission (PET and SPECT) and transmission (CT) tomographic reconstruction. This platform is a scalable software providing both basic image reconstruction features for…
free (w/ or w/o commercial version)… ImageJ (Image Processing and Analysis in Java) 1 Jan 201912 Aug 2020 ImageJ is a public domain Java image processing program inspired by NIH Image for the Macintosh. It runs, either as an online applet or as a downloadable application, on any…
free (w/ or w/o commercial version)… SIRF (Synergistic Image Reconstruction Framework) for Biomedical Imaging 1 Jan 201912 Aug 2020 The CCP (Collaborative Computational Project) in synergistic image reconstruction for biomedical imaging (SyneRBI), formerly known as CCP PET-MR (Collaborative Computational Project in synergistic PET-MR image reconstruction), project has led to…
NMMItools 