COMKAT is a MATLAB software for compartmental modeling oriented to nuclear medicine applications (PET & SPECT). It supports models of a wide range complexity including multiple injection, receptor model with saturation. It supports many image formats, including DICOM images. Using either the command line interface or GUI, models are easily specified, solved or used to fit experimental data. Sensitivity equations are supported. No mathematical derivations are required on the part of the user.
Tutorials: Link 1 (Introduction), Link 2 (Getting started), Link 3 (Examples) & Link 4 (Step-by-step guide)
NMMItools 
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