Research Software for Multi-Tracer PET Imaging and Kinetic Analysis
mfEVolve™ is a research-only software tool designed to facilitate multi-tracer and quantitative dynamic PET research studies by providing tools for processing, analyzing, and quantifying PET images.
- research-only software tool enabling multi-tracer PET studies
- research image database to store and organize research data supporting the DICOM, Analyze, IMX NIFTI and flat raw binary data, organization by custom groups , view/edit of DICOM attributes and de-identification of clinical data ,
- Oncology Module for multi-tracer PET Design and Processing,
- Kinetics Module for fast and robust compartment model fits with separable parameter space kinetic models of up to 3 tissue compartments and 5 rate parameters for each tracer, simultaneous fits in multi-tracer studies for up to 5 tracers, exhaustive search option for guaranteed best fits, full parametric image fits in seconds (for some model configurations),
- Image Display and Visualization of 2D and 3D volumetric images supporting Maximum Intensity Projection (MIP), zoom display with pixel replication/interpolation and image crosshair for rapid co-localization across all three dimensions in space,
- Image Overlay and rigid/non-rigid co-registration using linked or separate display color maps and fine-tuning of image alignment,
- Image Analysis Tool to draw and save 2D and 3D Regions-of-Interest (ROIs) and extract ROI statistics, measure time-activity curves (TACs) and display horizontal, vertical and temporal image profiles
- Dynamic Image Visualization to rapidly move across time frames and display (i) time-frame averages and single frames, (ii) early- or late-frame averages to visualize uptake and retention phases, and (iii) overlays of timeframe ranges to identify and manage patient motion during acquisition,
- Image Manipulations including shift, shear ad rotation in 3 image planes, adjustment of pixel size and slice thickness, bilinear and cubic interpolation, application or removal of decay correction, smoothing with a variety of filters an saving of the processed DICOM output images.
mfEVolve™ is a research-only software tool developed by MultiFunctional Imaging LLC. The tool has not been FDA approved or cleared for patient care. The user accepts all responsibility for use of this software and any use involving human subjects must meet all applicable institutional and federal requirements for human subjects research. It is offered for free for research use only and is intellectually protected by US Patents 7,484,556 and 10,175,216; (other patents may be pending).
YouTube Seminar on Multi-Tracer Kinetic Modeling (by Prof. Dan Kadrmas, President and CSO of MultiFunctional Imaging LLC & Emeritus Professor at University of Utah)
NMMItools 